Dr.  Christian Spengler

CV

2007 Completion of Secondary Education
2007 Studies of physics at saarland university
2010 Bachelor's Thesis "Ionic induced modification of surfaces"
2012-2013 Master
2013- Promotion

Publications

2024

• C. Spengler, E. Maikranz, B. Glatz, M.A. Klatt, H. Heintz, M. Bischoff, L. Santen, A. Fery, K. Jacobs:
  "The adhesion capability of Staphylococcus aureus cells is heterogeneously distributed over the cell envelope";
  Soft Matter 20 (2024) 484 DOI: 10.1039/d3sm01045g ⇒ Abstract
  Pressemitteilung [ ] PDF
  

2022

• J. Mischo, T. Faidt, R. B. McMillan, J. Dudek, G. Gunaratnam, P. Bayenat, A. Holtsch, C. Spengler, F. Müller, H. Hähl, M. Bischoff, M. Hannig, K. Jacobs:
  "Hydroxyapatite Pellets as Versatile Model Surfaces for Systematic Adhesion Studies on Enamel: A Force Spectroscopy Case Study";
  ACS Biomater. Sci. Eng. (2022) DOI: 10.1021/acsbiomaterials.1c00925 ⇒ Abstract
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2021

• J. Mischo, T. Faidt, R.B. McMillan, J. Dudek, G. Gunaratnam, P. Bayenat, A. Holtsch, C. Spengler, F. Mueller, H. Hähl, M. Bischoff, M. Hannig, K. Jacobs:
  "Hydroxyapatite pellets as versatile model surfaces for systematic studies on enamel";
  bioRxiv (2021) DOI: 10.1101/2021.01.11.426207 ⇒ Abstract
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• C. Spengler, B.A. Glatz, E. Maikranz, M. Bischoff, M.A. Klatt, L. Santen, A. Fery, K. Jacobs:
  "The adhesion capability of S. aureus cells is heterogeneously distributed over the cell envelope";
  bioRxiv (2021) DOI: 10.1101/2021.01.05.425282 ⇒ Abstract
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• C. Spengler, F. Nolle, N. Thewes, B. Wieland, P. Jung, M. Bischoff, K. Jacobs,:
  "Using Knock-Out Mutants to Investigate the Adhesion of Staphylococcus aureus to Abiotic Surfaces.";
  Int. J. Mol. Sci. 22 (2021) 11952 DOI: 10.3390/ijms222111952 ⇒ Abstract
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2020

• E. Maikranz, C. Spengler, N. Thewes, A. Thewes, F. Nolle, P. Jung, M. Bischoff, L. Santen, K. Jacobs:
  "Different binding mechanisms of Staphylococcus aureus to hydrophobic and hydrophilic surfaces";
  Nanoscale 12 (2020) 19267 DOI: 10.1039/d0nr03134h ⇒ Abstract
  [ ] Press coverage
  
• S. Kumari, G. Lang, E. DeSimone, C. Spengler, V. T. Trossmann, S. Lücker, M. Hudel, K. Jacobs, N. Krämer, T. Scheibel:
  "Data for microbe resistant engineered recombinant spider silk protein based 2D and 3D materials";
  Data in Brief 32 (2020) 106305 DOI: 10.1016/j.dib.2020.106305 ⇒ Abstract
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• S. Kumari, G. Lang, E. DeSimone, C. Spengler, V. T. Trossmann, S. Lücker, M. Hudel, K. Jacobs, N. Krämer, T. Scheibel:
  "Engineered spider silk-based 2D and 3D materials prevent microbial infestation";
  Materials Today 41 (2020) 21 DOI: 10.1016/j.mattod.2020.06.009 ⇒ Abstract
  [ ] Pressemitteilung
  
• P. Jung, C. E. Mischo, G. Gunaratnam, C. Spengler, S. L. Becker, B. Hube, K. Jacobs, M. Bischoff:
  "Candida albicans adhesion to central venous catheters: Impact of blood plasma-driven germ tube formation and pathogen-derived adhesins";
  Virulence 11 (2020) 1453 DOI: 10.1080/21505594.2020.1836902 ⇒ Abstract
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• D. W. Müller, A. Holtsch, S. Lößlein, C. Pauly, C. Spengler, S. Grandthyll, K. Jacobs, F. Mücklich, F. Müller:
  "In-depth investigation of copper surface chemistry modification by ultrashort pulsed direct laser interference pattering";
  Langmuir 36 (2020) 13415 DOI: 10.1021/acs.langmuir.0c01625 ⇒ Abstract
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• G. Gunaratnam, C. Spengler, S. Trautmann, P. Jung, J. Mischo, B. Wieland, C. Metz, S. Becker, M. Hannig, K. Jacobs, M. Bischoff:
  "Human blood plasma factors affect the adhesion kinetics of Staphylococcus aureus to central venous catheters";
  Scientific Reports 10 (2020) 20992 DOI: DOI 10.1038/s41598-020-77168-x ⇒ Abstract
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2019

• F. Müller, C. Spengler, T. Faidt, A. Holtsch, H. Hähl:
  "Comment on “Sonophotocatalytic degradation of textile dyes over Cuimpregnated ZnO catalyst in aqueous solution” by J. Shah et al.,Process Saf. Environ. Prot. 2018. 116 (2018) 149–158";
  Process. Saf. Environ. 129 (2019) 149 DOI: 10.1016/j.psep.2019.05.054 ⇒ Abstract
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• C. Spengler, F. Nolle, J. Mischo, T. Faidt, S. Grandthyll, N. Thewes, M. Koch, F. Müller, M. Bischoff, M. A. Klatt, K. Jacobs:
  "Strength of bacterial adhesion on nano-structured surfaces quantified by substrate morphometry ";
  Nanoscale 11 (2019) 19713 DOI: 10.1039/C9NR04375F ⇒ Abstract
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• G. Gunaratnam, L. Tuchscherr, M. I. Elhawy, R. Bertram, J. Eisenbeis, C. Spengler, T. Tschernig, B. Löffler, G. A. Somerville, K. Jacobs, M. Herrmann, M. Bischoff:
  "ClpC affects the intracellular survival capacity of Staphylococcus aureus in non-professional phagocytic cells";
  Sci. Rep. 9 (2019) 16267 ⇒ Abstract
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• G. Gunaratnam, P. Jung, J. Willeit, C. Spengler, K. Jacobs, M. Bischoff:
  "Probing the Adhesion Forces of Staphylococcus aureus to Central Venous Catheters by Single-Cell Force Spectroscopy";
  Microscopy and Microanalysis 25 (S1) (2019) 53 DOI: 10.1017/S1431927618015994 ⇒ Abstract
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2018

• F. Müller, S. Grandthyll, T. Faidt, C. Spengler, H. Hähl:
  "Comment on “XPS and FTIR studies of sodium arsenate vitrification by cullet” by Z. Zhao et al., J. Non-Cryst. Solids 452 (2016) 238–244";
  Journal of Non-Crystalline Solids 502 (2018) 253 ⇒ Abstract
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• T. Faidt , A. Friedrichs, S. Grandthyll, C. Spengler, K. Jacobs, F. Müller:
  "Effect of Fluoride Treatment on the Acid Resistance of Hydroxyapatite";
  Langmuir 34 (2018) 15253 ⇒ Abstract
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2017

• C. Spengler, N. Thewes, F. Nolle, T. Faidt, N. Umanskaya, M. Hannig, M. Bischoff, K. Jacobs:
  "Enhanced adhesion of Streptococcus mutans to hydroxyapatite after exposure to saliva";
  J. Mol. Recognit. 30 (2017) e2615 DOI: 10.1002/jmr.2615 ⇒ Abstract
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• C. Spengler, N. Thewes, Ph. Jung, M. Bischoff, and K. Jacobs:
  "Determination of the nano-scaled contact area of Staphylococcal cells";
  Nanoscale 9 (2017) 10084 ⇒ Abstract
  
  

2016

• C. Zeitz, T. Faidt, S. Grandthyll, H. Hähl, N. Thewes,C. Spengler, J. Schmauch, M. J. Deckarm, C. Gachot, H. Natter, M. Hannig, F. Müller, K. Jacobs:
  "Synthesis of hydroxyapatite substrates: bridging the gap between model surfaces and enamel";
  ACS Appl. Mater. Interfaces 8 (2016) 25848 ⇒ Abstract
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• B. Kann, C. Spengler, K. Coradini, L. A. Rigo, M.L. Bennink, K. Jacobs, H.L. Offerhaus, R.C R. Beck, M. Windbergs:
  "Intracellular Delivery of Poorly Soluble Polyphenols: Elucidating the Interplay of Self-Assembling Nanocarriers and Human Chondrocytes";
  Analytical Chemistry 88 (2016) 7014 ⇒ Abstract
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2015

• N. Thewes, P. Loskill, C. Spengler, S. Hümbert, M.Bischoff, K. Jacobs:
  "A detailed guideline for the fabrication of single bacterial probes used for atomic force spectroscopy (Open Access via SciDok)";
  Eur. Phys. J.E 38 (2015) 140 DOI: 10.22028/D291-31020 ⇒ Abstract
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